Tamoxifen linked to 82% increase in strokes

Wellness is a big part of my personal, as well as professional life. I’m going to begin posting lots of articles I’ve authored over the years on the subject of wellness, especially studies and insights that I think my family and friends need to know. Enjoy and be well! -Terry Rondberg

Tamoxifen linked to 82% increase in strokes

By Terry Rondberg, DC
More than 250,000 women in the United States are diagnosed with breast cancer each year and many are given the prescription tamoxifen. Recent studies, however, show that the drug Tamoxifen increases the risk of thromboembolism (a blood clot that has traveled from its site of origin to another vessel and therefore can increase the risk of stroke as much as 82%.

The research was published in Neurology, the scientific journal of the American Academy of Neurology (AAN). Researchers from Duke University Medical Center conducted a systematic review of all clinical trials of tamoxifen published since 1980 using MEDLINE.

Nine trials met their inclusion criteria, with 39,601 total subjects enrolled, 19,954 of whom were randomized to tamoxifen. Six of the trials specifically reported ischemic stroke events. All trials used a standard dose of tamoxifen (20 mg daily).

“With tamoxifen, we found the frequency of all strokes was 1.06% and for ischemic stroke was 0.71%, versus 0.39% with controls,” reported study author Cheryl Bushnell, MD, MHS. The risk of ischemic stroke increased by 82% and risk of all strokes by 29% in women randomized to tamoxifen versus placebo or other therapies.

Despite the uncontestable numbers reported in the study, the AAN distributed a press release saying the increase in risk was “slight,” and listing the supposed benefits of the drug before mentioning the research results.

SOURCE: “Risk of ischemic stroke with tamoxifen treatment for breast cancer: A meta-analysis,” Neurology: 63: 1230-1233

Winning the ‘Texas Humanitarian’ Award

Terry Rondberg wins Texas Humanitarian AwardOne of the main reasons I got into chiropractic was to help people and ease their pain. It’s still something that drives me today. When I look back on my career, one of the proudest moments was being presented with the Sterling Pruitt award. In a couple of weeks, it will be 11 years since I received the honor, but it still means a lot to me. And whatever I’m working on today, helping people remains at the forefront of my thoughts. Below is the original article announcing the award.

Dr. Terry Rondberg wins ‘Texas Humanitarian’ Award

Dr. Terry A. Rondberg, CEO of the World Chiropractic Alliance and publisher of The Chiropractic Journal, was presented with the prestigious “Sterling Pruitt Humanitarian Award,” by the Chiropractic Society of Texas (CST).

The award, presented on April 9, 1999, is named after one of Texas’ most beloved and respected chiropractic pioneers and is given “In appreciation of distinguished service to our fellow man in the interest of public health and for dedication to public health and for dedication to the sick and suffering of the State of Texas.”
According to Society spokesman R.J. Kelly, D.C., “This award is the highest honor given by the CST and recognizes the chiropractor who has done the most for the profession… It is our belief that Dr. Rondberg is truly a warrior and visionary in chiropractic and we are very proud to acknowledge him with this award.”

On a more personal note, Dr. Kelly said that, in regards to the Rondberg award, he was reminded of a remark coach Bum Phillips made describing Earl Campbell: “He may not be the only one in his class, but it doesn’t take long to call roll.”

Kelly added: “Terry Rondberg has not only been extraordinary at identifying problems within the profession, but also at doing something about them. He saw that we did not have a periodical that represented principled chiropractic, so he created one. He found there were no books on chiropractic for the lay public; he has now written several. Observing that there was no association to act as a watchdog for ‘the principles,’ he created the WCA. Discovering that there was no ethical congruent malpractice insurance available, Dr. Rondberg established CBS.”

The choice of Dr. Rondberg to receive the award was unusual since it is ordinarily given to doctors within the state of Texas. Dr. Sid Williams was another “non-Texan” to receive the award in the past.
In accepting the award, Rondberg said he was “incredibly moved by the honor, particularly since the state is filled with principled doctors who have gained a widespread reputation for their diligent defense of subluxation-based chiropractic.”

He noted that he was accepting it on behalf of all doctors who continue to uphold the principles of chiropractic, and will be motivated to continue his work to make subluxation-based chiropractic the number one health care choice of the new millennium.

Up close and personal